SCHEMBL27027433

SCHEMBL27027433

Cc1cc(OC2C(C)(C)C(NC(=O)c3ccc(C(C)C)cc3)C2(C)C)ccc1C#N

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 19/20 0.68
▸ S1PR3 Q99500 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24031675 1.00 AR (0.68) ARS1PR3
SCHEMBL17517173 0.90 AR (0.71) AR
SCHEMBL26802426 0.89 AR (0.73) AR
SCHEMBL24031674 0.89 AR (0.56) ARS1PR3
SCHEMBL23594178 0.88 AR (0.55) ARS1PR3
SCHEMBL27027588 0.86 AR (0.70) AR
SCHEMBL17517171 0.86 AR (0.70) AR
SCHEMBL20436960 0.84 AR (0.49) AR
SCHEMBL26804901 0.84 AR (0.68) AR
SCHEMBL26804962 0.83 AR (0.70) ARS1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018149-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE ANHORN MEDICINES CO., LTD. (TW) 2024-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018149-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE MDM2, PSMG3, ADRM1 AR 2577/4885S1PR3 4829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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