Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EDNRB | P24530 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27030595 | 0.90 | EDNRA (0.61) | EDNRAMEN1KMT2AEDNRBKDM4E | |
| SCHEMBL27245351 | 0.85 | NR1H3 (0.64) | EDNRATSHR | |
| SCHEMBL29944893 | 0.85 | NR1H3 (0.64) | EDNRATSHR | |
| SCHEMBL12293623 | 0.81 | PPARG (0.58) | EDNRAKDM4EWDR5FABP4FABP5 | |
| SCHEMBL4631551 | 0.80 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL12293612 | 0.80 | MEN1 (0.76) | EDNRAMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL12293616 | 0.78 | MEN1 (0.57) | EDNRAMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL27245384 | 0.78 | NR1H3 (0.63) | EDNRAMEN1KMT2ATSHREDNRB | |
| SCHEMBL29944956 | 0.78 | NR1H3 (0.63) | EDNRAMEN1KMT2ATSHREDNRB | |
| SCHEMBL533208 | 0.78 | EDNRA (0.62) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308554-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING TYPE 2 DIABETES AND DEMENTIA | The Board of Trustees of the University of Illinois (US) | 2024-01-24 | — | — | EP | disclosed |