SCHEMBL2703294

SCHEMBL2703294

O=CN[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.54
NAALAD2 Q9Y3Q0 1/20 0.54
SLC7A5 Q01650 1/20 0.51
MME P08473 5/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ACE P12821 7/20 0.49
CPA1 P15085 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
EPHX1 P07099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4611286 1.00 FOLH1 (0.54) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL3799467 1.00 FOLH1 (0.54) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL10494110 0.98 FOLH1 (0.52) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL10494109 0.98 FOLH1 (0.52) FOLH1NAALAD2SLC7A5MMEMEN1
Trifluoroacetic Acid SCHEMBL29695528 0.92 ACE (0.53) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL10537166 0.91 FOLH1 (0.47) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL9052244 0.86 FOLH1 (0.43) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL697901 0.86 EPHX1 (0.61) FOLH1NAALAD2MMEMEN1KMT2A
SCHEMBL697900 0.86 EPHX1 (0.61) FOLH1NAALAD2MMEMEN1KMT2A
SCHEMBL8211678 0.86 EPHX1 (0.61) FOLH1NAALAD2MMEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118883955-A Alzheimer's disease biomarker and application thereof in early diagnosis 南方医科大学珠江医院 2024-11-01 CN claimed
CN-114796048-A Preparation and application of traditional Chinese medicine extract for preparing antioxidant 宿迁市中医院 2022-07-29 CN claimed
US-20120172293-A1 PEPTIDE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED 2012-07-05 US claimed
EP-2450374-A1 PEPTIDE AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2012-05-09 EP claimed
EP-1621546-B1 Peptide ligands specific to immonoglobulins TECNOGEN SPA (IT) 2008-10-29 EP claimed
CN-101160525-A Genetic code increase of non-natural active amino acid SCRIPPS RESEARCH INST (US) 2008-04-09 CN claimed
EP-1621546-A1 Peptide ligands specific to immonoglobulins TECNOGEN S.C.P.A. (IT) 2006-02-01 EP claimed
US-20040261198-A1 Restructuring and finishing of keratin fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-30 US claimed
CN-1031051-C Cycloalkyl-substituted glutaramide antihypertensive agents PFIZER (US) 1996-02-21 CN claimed
US-5122461-A Reacting monophenolic compounds with oxygen in presence of monophenol monooxygenase and metal ions; product stabilized by complexing with metals; increasing DOPA yield INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1992-06-16 US claimed
US-4789757-A N-formylation of amino carboxylic compounds with formamide W. R. GRACE & CO.-CONN. (US) 1988-12-06 US claimed
JP-57058626-A None JP disclosed
WO-2025049431-A2 CONTROL OF FLUX TOWARD 2-PHENYLETHANOL PRODUCTION INSCRIPTA, INC. (US) 2025-03-06 WO disclosed
CN-119331778-A Lactic acid bacteria composition for adjuvant treatment of diabetes and composite lactic acid bacteria probiotic and application thereof 均瑶润盈生物科技(上海)有限公司 2025-01-21 CN disclosed
CN-118883955-A Alzheimer's disease biomarker and application thereof in early diagnosis 南方医科大学珠江医院 2024-11-01 CN disclosed
WO-1999024604-A1 METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE BIO MERIEUX (FR) 1999-05-20 WO disclosed
US-5122461-A Reacting monophenolic compounds with oxygen in presence of monophenol monooxygenase and metal ions; product stabilized by complexing with metals; increasing DOPA yield INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1992-06-16 US disclosed
US-4801742-A N-formylation of amino carboxylates with alkyl formates W. R. GRACE & CO.-CONN. (US) 1989-01-31 US disclosed
JP-S5758626-A CARCINOSTATIC AGENT RIKAGAKU KENKYUSHO 1982-04-08 JP disclosed
US-4171225-A HYDROXYMETHYL AMINO ALKYLCARBOXYLIC OR -SULFONIC ACID ALKALI SALTS AS STABLE REDUCING AGENTS U.S. PHILIPS CORPORATION (US) 1979-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172293-A1 PEPTIDE AND USE THEREOF GLP1R, GIPR, SCTR FOLH1 723/4885NAALAD2 1944/4885SLC7A5 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.