SCHEMBL3799467

SCHEMBL3799467

O=CNC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.54
NAALAD2 Q9Y3Q0 1/20 0.54
SLC7A5 Q01650 1/20 0.51
MME P08473 5/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ACE P12821 7/20 0.49
CPA1 P15085 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
EPHX1 P07099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4611286 1.00 FOLH1 (0.54) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL2703294 1.00 FOLH1 (0.54) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL10494110 0.98 FOLH1 (0.52) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL10494109 0.98 FOLH1 (0.52) FOLH1NAALAD2SLC7A5MMEMEN1
Trifluoroacetic Acid SCHEMBL29695528 0.92 ACE (0.53) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL10537166 0.91 FOLH1 (0.47) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL9052244 0.86 FOLH1 (0.43) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL697901 0.86 EPHX1 (0.61) FOLH1NAALAD2MMEMEN1KMT2A
SCHEMBL697900 0.86 EPHX1 (0.61) FOLH1NAALAD2MMEMEN1KMT2A
SCHEMBL8211678 0.86 EPHX1 (0.61) FOLH1NAALAD2MMEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118883955-A Alzheimer's disease biomarker and application thereof in early diagnosis 南方医科大学珠江医院 2024-11-01 CN claimed
US-4725582-A IMMUNE RESPONSE ENHANCERS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1988-02-16 US claimed
CN-119331778-A Lactic acid bacteria composition for adjuvant treatment of diabetes and composite lactic acid bacteria probiotic and application thereof 均瑶润盈生物科技(上海)有限公司 2025-01-21 CN disclosed
CN-118883955-A Alzheimer's disease biomarker and application thereof in early diagnosis 南方医科大学珠江医院 2024-11-01 CN disclosed
EP-4267193-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF Ludwig-Maximilians-Universität München (DE) 2023-11-01 EP disclosed
WO-2022136555-A9 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-09-22 WO disclosed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 WO disclosed
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-23 US disclosed
EP-2675487-B1 NON-INVASIVE IN VIVO METHODS OF MONITORING BIODISTRIBUTION WITH RADIOLABELED COMPOUNDS BOVIN NICOLAI VLADIMIROVICH (RU) 2018-10-17 EP disclosed
US-10071990-B2 Site-specific orthogonal labeling of the carboxy terminus of α-tubulin in live cells THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2018-09-11 US disclosed
US-10040823-B2 In vivo methods of monitoring biodistribution KODE BIOTECH LIMITED (NZ) 2018-08-07 US disclosed
EP-2675487-A1 IN VIVO METHODS OF MONITORING BIODISTRIBUTION Bovin, Nicolai Vladimirovich (RU) 2013-12-25 EP disclosed
WO-2013096823-A1 CATIONIC PEPTIDES AND USE OF SUCH PEPTIDES FOR INHIBITING EXOTOXIN PRODUCTION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2013-06-27 WO disclosed
WO-2012121610-A1 IN VIVO METHODS OF MONITORING BIODISTRIBUTION BOVIN NIKOLAI VLADIMIROVICH (RU) 2012-09-13 WO disclosed
EP-2454229-A1 AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN Kong, Xianqi (CA) 2012-05-23 EP disclosed
WO-2010127439-A1 AMMO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) 2010-11-11 WO disclosed
EP-1841460-A2 THERAPEUTIC FORMULATIONS FOR THE TREATMENT OF BETA-AMYLOID RELATED DISEASES Neurochem (International) Limited (CH) 2007-10-10 EP disclosed
WO-2007049098-A2 THERAPEUTIC FORMULATIONS FOR THE TREATMENT OF BETA-AMYLOID RELATED DISEASES NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-05-03 WO disclosed
EP-1644325-A2 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES Neurochem (International) Limited (CH) 2006-04-12 EP disclosed
WO-2004113275-A2 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2004-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040823-B2 In vivo methods of monitoring biodistribution FABP1, FUCA1, LIPA FOLH1 22/4885NAALAD2 373/4885SLC7A5 18/4885
US-10071990-B2 Site-specific orthogonal labeling of the carboxy terminus of α-tubulin in live cells TUBB, TUBA1C, TUBB1 FOLH1 220/4885NAALAD2 93/4885SLC7A5 2719/4885
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF TUBB6, GALNT10, TUBB FOLH1 120/4885NAALAD2 219/4885SLC7A5 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.