Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PCNA | P12004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2703294 | 0.91 | FOLH1 (0.54) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL3799467 | 0.91 | FOLH1 (0.54) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL4611286 | 0.91 | FOLH1 (0.54) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL10494110 | 0.90 | FOLH1 (0.52) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL10494109 | 0.90 | FOLH1 (0.52) | FOLH1NAALAD2MMEACECPA1 | |
| Trifluoroacetic Acid SCHEMBL29695528 | 0.84 | ACE (0.53) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL28732225 | 0.84 | FOLH1 (0.50) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL188398 | 0.82 | FOLH1 (0.49) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL21598075 | 0.82 | FOLH1 (0.52) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL21598076 | 0.82 | FOLH1 (0.52) | FOLH1NAALAD2MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820860-A | Novel thyronine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-11 | — | — | US | disclosed |