Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367057 | 0.83 | NOTUM (0.55) | NOTUMADRB1KDM4EALDH1A1LMNA | |
| SCHEMBL4538317 | 0.82 | NOTUM (0.57) | NOTUMADRB1KDM4EALDH1A1PLA2G1B | |
| SCHEMBL28396664 | 0.77 | ADRB1 (0.71) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL3957609 | 0.75 | KEAP1 (0.53) | KDM4EALDH1A1RAB9ALMNAHTT | |
| SCHEMBL14704616 | 0.75 | ADRB1 (0.56) | NOTUMADRB1KDM4EALDH1A1PLA2G1B | |
| SCHEMBL23291707 | 0.73 | GAA (0.39) | ALDH1A1LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL30787766 | 0.73 | NOTUM (0.39) | NOTUMADRB1HTR1ADRD2DRD4 | |
| SCHEMBL22584622 | 0.73 | NOTUM (0.39) | NOTUMADRB1HTR1ADRD2DRD4 | |
| SCHEMBL1825806 | 0.73 | ADRB1 (0.65) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL30407939 | 0.73 | ADRB1 (0.65) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017178-A1 | SUBSTITUTED HYDANTOIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | AVITAR BIOSCIENCES, INC. (CN) | 2024-01-25 | — | — | WO | disclosed |