Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035204 | 0.87 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27035294 | 0.87 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27035210 | 0.86 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27035097 | 0.85 | TSHR (0.57) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27035133 | 0.85 | MAPT (0.65) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27035277 | 0.85 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27034989 | 0.83 | ALDH1A1 (0.68) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL26232436 | 0.81 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27035286 | 0.80 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27035160 | 0.80 | SIRT2 (0.58) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554567-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | Anadolu Universitesi (TR) | 2025-05-21 | — | — | EP | claimed |
| WO-2024019685-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | ANADOLU UNIVERSITESI (TR) | 2024-01-25 | — | — | WO | claimed |
| EP-4554567-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | Anadolu Universitesi (TR) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024019685-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | ANADOLU UNIVERSITESI (TR) | 2024-01-25 | — | — | WO | disclosed |