Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035148 | 0.87 | ALDH1A1 (0.65) | ALDH1A1GAALMNATSHRSMN1; SMN2 | |
| SCHEMBL27035204 | 0.84 | SMN1; SMN2 (0.56) | ALDH1A1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL27035097 | 0.83 | TSHR (0.57) | ALDH1A1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL27035133 | 0.83 | MAPT (0.65) | ALDH1A1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL27034997 | 0.83 | NPC1 (0.67) | ALDH1A1LMNASMN1; SMN2HTTSIRT2 | |
| SCHEMBL7952282 | 0.80 | SIRT2 (0.72) | ALDH1A1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL29376403 | 0.80 | HTR1A (0.71) | ALDH1A1GAALMNATSHRSMN1; SMN2 | |
| SCHEMBL27035277 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1LMNATSHRSMN1; SMN2SIRT2 | |
| SCHEMBL8900040 | 0.78 | LMNA (0.66) | ALDH1A1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL17513948 | 0.78 | SIRT2 (0.65) | ALDH1A1LMNATSHRSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554567-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | Anadolu Universitesi (TR) | 2025-05-21 | — | — | EP | claimed |
| WO-2024019685-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | ANADOLU UNIVERSITESI (TR) | 2024-01-25 | — | — | WO | claimed |
| EP-4554567-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | Anadolu Universitesi (TR) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024019685-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | ANADOLU UNIVERSITESI (TR) | 2024-01-25 | — | — | WO | disclosed |