SCHEMBL270356

SCHEMBL270356

CP(c1ccccc1)c1ccccc1.c1ccc(Pc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.60
ESR2 Q92731 4/20 0.60
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18044168 1.00 ESR1 (0.60) ESR1ESR2CYP3A4TDP1
SCHEMBL10655664 0.85 ESR1 (0.43) ESR1ESR2CYP3A4TDP1
SCHEMBL11648324 0.84 ESR1 (0.70) ESR1ESR2CYP3A4TDP1
SCHEMBL40441 0.84 ESR1 (0.70) ESR1ESR2CYP3A4TDP1
Phosphine SCHEMBL3757269 0.81 ESR1 (0.67) ESR1ESR2CYP3A4TDP1
SCHEMBL9356953 0.81 ESR1 (0.67) ESR1ESR2CYP3A4TDP1
SCHEMBL11420354 0.81 ESR1 (0.67) ESR1ESR2CYP3A4TDP1
SCHEMBL3962149 0.81 ESR1 (0.75) ESR1ESR2CYP3A4TDP1
SCHEMBL2046588 0.81 ESR1 (0.67) ESR1ESR2CYP3A4TDP1
SCHEMBL31123062 0.81 ESR1 (0.67) ESR1ESR2CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117531994-A Binuclear silver nanocluster with accurate atoms and preparation method thereof 福建师范大学 2024-02-09 CN claimed
CN-117327007-A VT107 preparation method 上海陶术生物科技有限公司 2024-01-02 CN claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-116037183-A Preparation method of high-performance photocatalytic nitrogen fixation catalyst 广州大学 2023-05-02 CN claimed
CN-112803083-A Zinc ion battery containing zinc complex 江苏师范大学 2021-05-14 CN claimed
JP-4795589-B2 2011-10-19 JP claimed
EP-1272500-B1 PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES ABBOTT LAB (US) 2005-05-04 EP claimed
EP-1272500-A2 PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES Abbott Laboratories (US) 2003-01-08 EP claimed
US-6437106-B1 ALKYLATION WITH ALKENYL CARBONATE OR CARBAMATE IN PRESENCE OF PALLADIUM CATALYST AND PHOSPHINE; CYCLIZATION ABBOTT LABORATORIES 2002-08-20 US claimed
WO-2000078773-A2 PROCESS FOR PREPARING 6-O-ALKENYL-SUBSTITUTED ERYTHROMYCIN DERIV ATIVES ABBOTT LABORATORIES (US) 2000-12-28 WO claimed
EP-0172324-B1 RESIN ENCAPSULATION TYPE SEMICONDUCTOR DEVICE BY USE OF EPOXY RESIN COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 1991-04-17 EP claimed
US-4609639-A IRON AND PALLADIUM ATOCHEM (FR) 1986-09-02 US claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US disclosed
CN-112803083-A Zinc ion battery containing zinc complex 江苏师范大学 2021-05-14 CN disclosed
EP-3194409-B1 PYRIDINE COMPLEX OF ZIRCONIUM, CATALYTIC SYSTEM COMPRISING SAID PYRIDINE COMPLEX OF ZIRCONIUM AND PROCESS OF (CO)POLYMERIZATION OF CONJUGATED DIENES VERSALIS SPA (IT) 2019-09-11 EP disclosed
US-10059724-B2 Pyridine complex of zirconium, catalytic system comprising said pyridine complex of zirconium and process of (co)polymerization of conjugated dienes VERSALIS S.P.A. (IT) 2018-08-28 US disclosed
US-4902833-A Bisphosphine dioxides UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-02-20 US disclosed
US-4609639-A IRON AND PALLADIUM ATOCHEM (FR) 1986-09-02 US disclosed
US-4609639-A IRON AND PALLADIUM ATOCHEM (FR) 1986-09-02 US disclosed
EP-0055618-B1 CARBONYLATION PROCESS EMPLOYING A CATALYST STABILISED IN SOLUBLE FORM MONSANTO COMPANY (US) 1985-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10059724-B2 Pyridine complex of zirconium, catalytic system comprising said pyridine complex of zirconium and process of (co)polymerization of conjugated dienes SOD1, POR, NOX4 ESR1 1915/4885ESR2 3836/4885CYP3A4 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.