Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 10/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 9/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27036629 | 0.87 | CCR4 (0.40) | CCR4CD274PDCD1PDCD1LG2 | |
| SCHEMBL27080875 | 0.82 | CD274 (0.44) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29983940 | 0.82 | CD274 (0.44) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23725212 | 0.80 | CD274 (0.41) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29984282 | 0.78 | PDCD1LG2 (0.40) | CCR4CD274PDCD1LG2 | |
| SCHEMBL27036467 | 0.78 | PDCD1LG2 (0.40) | CCR4CD274PDCD1LG2 | |
| SCHEMBL25171806 | 0.78 | CD274 (0.44) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29144140 | 0.77 | CD274 (0.46) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29144011 | 0.77 | SQOR (0.48) | CD274PDCD1 | |
| SCHEMBL29143920 | 0.74 | CD274 (0.45) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024018403-A1 | SUBSTITUTED IMIDAZOAMIDE COMPOUNDS, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-01-25 | — | — | WO | disclosed |