SCHEMBL27037294

SCHEMBL27037294

C#Cc1cnc(NC)c2cnc(C3(C(N)=O)CC3)cc12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ NNMT P40261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473753 1.00 NNMT (0.30) NNMT
SCHEMBL31473790 0.92 — —
SCHEMBL31473861 0.88 KDM4E (0.34) NNMT
SCHEMBL31473797 0.88 PGK1 (0.33) —
SCHEMBL31473656 0.85 BACE1 (0.31) —
SCHEMBL31473632 0.84 — —
SCHEMBL27037721 0.82 NNMT (0.32) NNMT
SCHEMBL30698968 0.82 NNMT (0.32) NNMT
SCHEMBL31473839 0.81 NNMT (0.31) NNMT
SCHEMBL31473805 0.81 NNMT (0.35) NNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 NNMT 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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