Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.49 |
| ▸ | ULK1 | O75385 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27040326 | 0.99 | DDB1 (0.48) | DDB1CRBNULK1SIRT2PRKCQ | |
| SCHEMBL27039385 | 0.80 | PTPN2 (0.65) | DDB1CRBNALDH1A1ABL1LMNA | |
| Hydrochloric Acid SCHEMBL30828432 | 0.77 | CRBN (0.56) | DDB1CRBNALDH1A1AURKBKDM4E | |
| SCHEMBL27039404 | 0.76 | PTPN1 (0.45) | DDB1CRBNABL1 | |
| SCHEMBL24481148 | 0.76 | CRBN (0.55) | DDB1CRBNALDH1A1LMNAKDM4E | |
| SCHEMBL22144563 | 0.75 | CRBN (0.58) | DDB1CRBN | |
| SCHEMBL2717891 | 0.74 | ULK1 (0.60) | ULK1SIRT2FLT3LMNAKDM4E | |
| SCHEMBL29794453 | 0.74 | DDB1 (0.50) | DDB1CRBNALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL22119523 | 0.74 | CRBN (0.56) | DDB1CRBNHPGD | |
| Acetic Acid SCHEMBL7374818 | 0.73 | ALDH1A1 (0.55) | SIRT2ITGB3ITGA2BALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558495-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | Bristol-Myers Squibb Company (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020084-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-25 | — | — | WO | disclosed |