SCHEMBL2704321

SCHEMBL2704321

CCCCCCCCCCCC(=S)SCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.56
PPARG P37231 7/20 0.56
PPARD Q03181 7/20 0.56
PPARA Q07869 7/20 0.56
HDAC11 Q96DB2 5/20 0.56
TSHR P16473 4/20 0.56
PTPN1 P18031 3/20 0.56
ALDH1A1 P00352 2/20 0.56
TLR2 O60603 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
FABP4 P15090 2/20 0.56
HSD17B10 Q99714 2/20 0.56
KMT2A Q03164 2/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
MEN1 O00255 1/20 0.56
ESR1 P03372 1/20 0.56
ALOX15 P16050 1/20 0.56
PDE4A P27815 1/20 0.56
PDE3A Q14432 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574534 0.83 GPR84 (0.60) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL10911110 0.79 GPR84 (0.46) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL11175379 0.79 GPR84 (0.46) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL10911077 0.79 GPR84 (0.46) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL11243793 0.77 GPR84 (0.44) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL10928366 0.76 AKR1B1 (0.44) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL11484034 0.74 AKR1B1 (0.42) GPR84PPARGPPARDPPARAHDAC11
Dotriacontanoic Acid SCHEMBL25298401 0.73 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL25287435 0.73 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL25281884 0.73 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638064-B1 CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR SANDOZ AG (AT) 2021-07-21 EP disclosed
US-10106828-B2 Cell culture medium and process for protein expression, said medium and process comprising a PAM inhibitor SANDOZ GMBH (AT) 2018-10-23 US disclosed
US-20150267238-A1 Cell Culture Medium And Process For Protein Expression, Said Medium And Process Comprising A Pam Inhibitor SANDOZ GMBH (AT) 2015-09-24 US disclosed
US-9062337-B2 Cell culture medium and process for protein expression, said medium and process comprising a PAM inhibitor SANDOZ GMBH (AT) 2015-06-23 US disclosed
US-20130337506-A1 CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR SANDOZ GMBH (AT) 2013-12-19 US disclosed
EP-2638064-A2 CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR SANDOZ GMBH (AT) 2013-09-18 EP disclosed
WO-2012062810-A2 CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR SANDOZ GMBH (AT) 2012-05-18 WO disclosed
EP-2450375-A1 Cell culture medium and process for protein expression, said medium and process comprising a PAM inhibitor SANDOZ GMBH (AT) 2012-05-09 EP disclosed