SCHEMBL27043232

SCHEMBL27043232

N=C(N)NCCCC(NN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GNPAT O15228 3/20 0.46
ALOX15 P16050 1/20 0.38
C3AR1 Q16581 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DDAH1 O94760 1/20 0.36
FOLH1 Q04609 3/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
OTC P00480 1/20 0.35
NPY4R P50391 4/20 0.34
NPY1R P25929 3/20 0.34
NPY2R P49146 3/20 0.34
NPY5R Q15761 3/20 0.34
GAA P10253 1/20 0.33
NOD1 Q9Y239 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL408774 1.00 GNPAT (0.46) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL7196910 1.00 GNPAT (0.46) GNPATALOX15C3AR1MEN1KMT2A
Hydrochloric Acid SCHEMBL18222331 0.98 GNPAT (0.45) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL8663718 0.95 GNPAT (0.45) GNPATALOX15MEN1KMT2ACYP1A2
SCHEMBL8662167 0.95 GNPAT (0.45) GNPATALOX15MEN1KMT2ACYP1A2
SCHEMBL29836396 0.87 ALOX15 (0.39) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL30068909 0.87 ALOX15 (0.39) GNPATALOX15C3AR1MEN1KMT2A
Arginine SCHEMBL9124153 0.86 GSR (0.53) GNPATDDAH1FOLH1OTCNPY4R
SCHEMBL12971304 0.86 C3AR1 (0.43) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL8164682 0.86 C3AR1 (0.40) GNPATALOX15C3AR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107987166-A For the monoclonal antibody of the optimization of tissue factor approach restrainer (TFPI) 拜耳医药保健有限公司 2018-05-04 CN claimed
EP-4310093-A1 AMINO ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS, COMPRISING SAME Prazertherapeutics Inc. (KR) 2024-01-24 EP disclosed
CN-107106679-A anti-TREM 2 antibodies and methods of use thereof 艾利妥 2017-08-29 CN disclosed
CN-106714909-A Bruton's tyrosine kinase inhibitor combination and application thereof 药品循环有限责任公司 2017-05-24 CN disclosed
CN-102712687-A MASP isoforms as inhibitors of complement activation RIGSHOSPITALET 2012-10-03 CN disclosed