SCHEMBL408774

SCHEMBL408774

N=C(N)NCCC[C@H](NN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GNPAT O15228 3/20 0.46
ALOX15 P16050 1/20 0.38
C3AR1 Q16581 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DDAH1 O94760 1/20 0.36
FOLH1 Q04609 3/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
OTC P00480 1/20 0.35
NPY4R P50391 4/20 0.34
NPY1R P25929 3/20 0.34
NPY2R P49146 3/20 0.34
NPY5R Q15761 3/20 0.34
GAA P10253 1/20 0.33
NOD1 Q9Y239 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7196910 1.00 GNPAT (0.46) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL27043232 1.00 GNPAT (0.46) GNPATALOX15C3AR1MEN1KMT2A
Hydrochloric Acid SCHEMBL18222331 0.98 GNPAT (0.45) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL8663718 0.95 GNPAT (0.45) GNPATALOX15MEN1KMT2ACYP1A2
SCHEMBL8662167 0.95 GNPAT (0.45) GNPATALOX15MEN1KMT2ACYP1A2
SCHEMBL29836396 0.87 ALOX15 (0.39) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL30068909 0.87 ALOX15 (0.39) GNPATALOX15C3AR1MEN1KMT2A
Arginine SCHEMBL9124153 0.86 GSR (0.53) GNPATDDAH1FOLH1OTCNPY4R
SCHEMBL12971304 0.86 C3AR1 (0.43) GNPATALOX15C3AR1MEN1KMT2A
SCHEMBL8164682 0.86 C3AR1 (0.40) GNPATALOX15C3AR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
WO-2024161038-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY IMMUSMOL SAS (FR) 2024-08-08 WO claimed
CN-117644702-B High-performance plastic woven cloth and preparation thereof 保定龙军建材有限公司 2024-04-09 CN claimed
CN-117644702-A High-performance plastic woven cloth and preparation thereof 保定龙军建材有限公司 2024-03-05 CN claimed
US-20230220387-A1 D-SERINE TRANSPORT MODIFIER AND SCREENING METHOD THEREOF, AND SCREENING METHOD OF D-SERINE TRANSPORTER PROTEIN KAGAMI INC. (JP) 2023-07-13 US claimed
CN-107513103-B MASP isoforms as inhibitors of complement activation OMEROS CORP. (US) 2026-05-26 CN disclosed
WO-2026099761-A1 PEPTIDES SALEM YAHYA AHMED (EG) 2026-05-15 WO disclosed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP disclosed
WO-2025122600-A1 COMPOSITIONS AND METHODS FOR TREATING ABERRANT NITROSYLATION CASE WESTERN RESERVE UNIVERSITY (US) 2025-06-12 WO disclosed
WO-2024161038-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY IMMUSMOL SAS (FR) 2024-08-08 WO disclosed
CN-117644702-B High-performance plastic woven cloth and preparation thereof 保定龙军建材有限公司 2024-04-09 CN disclosed
CN-117644702-A High-performance plastic woven cloth and preparation thereof 保定龙军建材有限公司 2024-03-05 CN disclosed
US-7018826-B1 Particles for gene therapy ISLAND PHARMACEUTICALS LTD. (GB) 2006-03-28 US disclosed
US-6127421-A INJECTED OR DIFFUSED INTO THE EGG; POULTRY; VETERINARY MEDICINE; ASCITES FLUID IN THE ABDOMEN OF THE BIRD THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2000-10-03 US disclosed
US-5922713-A Inhibition of nitric oxide synthase WERNER ERNST (AT) 1999-07-13 US disclosed
US-5895788-A ASCITES IN POULTRY THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 1999-04-20 US disclosed
US-5439938-A Treating priapism by applying to erect penis an inhibitor of NO synthetase to cause penis to become flaccid THE JOHNS HOPKINS UNIVERSITY (US) 1995-08-08 US disclosed
US-5260373-A Immobilized immunoglobulin-binding proteins REPLIGEN CORPORATION (US) 1993-11-09 US disclosed
US-5089605-A For purification of monoclonal antibodies REPLIGEN CORPORATION (US) 1992-02-18 US disclosed
EP-0282308-A2 Immobilized immunoglobulin-binding proteins REPLIGEN CORPORATION (US) 1988-09-14 EP disclosed