Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045704 | 0.85 | PTGS2 (0.52) | ALDH1A1PTGDR2KMT2AKDM4ENPC1 | |
| SCHEMBL27045589 | 0.84 | ALDH1A1 (0.41) | ALDH1A1PKMPTGDR2HTTGAA | |
| SCHEMBL27045677 | 0.83 | PTGS2 (0.41) | ALDH1A1PKMPTGDR2GAAKMT2A | |
| SCHEMBL27045675 | 0.81 | PTGS2 (0.43) | ALDH1A1PTGDR2KMT2AKDM4ENPC1 | |
| SCHEMBL27045678 | 0.78 | KMT2A (0.49) | ALDH1A1HTTGAAKMT2AKDM4E | |
| SCHEMBL27045673 | 0.77 | CNR2 (0.35) | PTGDR2KMT2APTGS2MEN1POLB | |
| SCHEMBL27045812 | 0.76 | EGLN2 (0.42) | ALDH1A1PKMPTGDR2HTTGAA | |
| SCHEMBL27045236 | 0.75 | PTGDR2 (0.42) | ALDH1A1PKMPTGDR2HTTGAA | |
| SCHEMBL27045699 | 0.73 | PTGDR2 (0.43) | ALDH1A1PKMPTGDR2HTTKMT2A | |
| SCHEMBL27046426 | 0.72 | ALDH1A1 (0.56) | ALDH1A1PKMPTGDR2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |