Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045865 | 0.86 | APP (0.36) | APPACHE | |
| SCHEMBL27045800 | 0.80 | EPHX2 (0.34) | SLC6A4 | |
| SCHEMBL28300419 | 0.80 | RAPGEF4 (0.38) | FLT1MAP2K1TAS1R3TAS1R1TUBB1 | |
| SCHEMBL27045679 | 0.78 | FFAR4 (0.33) | APPACHE | |
| SCHEMBL27045746 | 0.77 | PGK1 (0.36) | APPLMNA | |
| SCHEMBL27049106 | 0.77 | LRRK2 (0.39) | — | |
| SCHEMBL24463622 | 0.72 | — | — | |
| SCHEMBL27045747 | 0.72 | TTR (0.36) | — | |
| SCHEMBL27045685 | 0.69 | APP (0.38) | FLT1APPTAS1R3TAS1R1LMNA | |
| SCHEMBL25153444 | 0.69 | TAAR1 (0.47) | APPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310084-A1 | PYRIDOPYRIMIDINE-BASED COMPOUND AND APPLICATION THEREOF | Jinan University (CN) | 2024-01-24 | — | — | EP | disclosed |