Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | XIAP | P98170 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045683 | 0.90 | PTGS2 (0.45) | PTGS2XIAPKMT2AALDH1A1MAPT | |
| SCHEMBL27045988 | 0.89 | PTGS2 (0.56) | PTGS2XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL27045686 | 0.89 | PTGS2 (0.40) | PTGS2XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL27045568 | 0.86 | MAPT (0.53) | PTGS2XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL27045181 | 0.85 | PTGDR2 (0.42) | KMT2AMEN1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL27045180 | 0.85 | PTGDR2 (0.42) | KMT2AMEN1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL27045819 | 0.85 | PTGDR2 (0.42) | KMT2AMEN1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL27046124 | 0.82 | PTGS2 (0.46) | PTGS2XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL27045583 | 0.82 | MEN1 (0.36) | PTGS2XIAPKMT2AMEN1PTGDR2 | |
| SCHEMBL27045590 | 0.80 | PTGS2 (0.46) | PTGS2XIAPKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |