Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045590 | 0.90 | PTGS2 (0.46) | PTGS2PTGDR2HMGCRATAD2XIAP | |
| SCHEMBL27045689 | 0.90 | PTGS2 (0.51) | PTGS2PTGDR2XIAPADORA2AADORA1 | |
| SCHEMBL27045686 | 0.89 | PTGS2 (0.40) | PTGS2PTGDR2XIAPKDM4EALDH1A1 | |
| SCHEMBL27045504 | 0.87 | ALDH1A1 (0.45) | PTGS2PTGDR2ATAD2XIAPKDM4E | |
| SCHEMBL27046116 | 0.85 | ATAD2 (0.39) | PTGS2ATAD2XIAPADORA3ADORA2A | |
| SCHEMBL27045580 | 0.81 | PTGS2 (0.46) | PTGS2PTGDR2ATAD2XIAPDHODH | |
| SCHEMBL27045181 | 0.80 | PTGDR2 (0.42) | PTGDR2HMGCRKDM4EALDH1A1POLB | |
| SCHEMBL27045988 | 0.80 | PTGS2 (0.56) | PTGS2PTGDR2XIAPADORA2AADORA1 | |
| SCHEMBL27045180 | 0.80 | PTGDR2 (0.42) | PTGDR2HMGCRKDM4EALDH1A1POLB | |
| SCHEMBL27045819 | 0.80 | PTGDR2 (0.42) | PTGDR2HMGCRKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |