Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045512 | 0.82 | MEN1 (0.53) | KMT2ALMNAMEN1ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL3174446 | 0.79 | LMNA (0.57) | KMT2ALMNAMAPK1MEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3173310 | 0.78 | ALDH1A1 (0.57) | KMT2ALMNAMAPK1MEN1ALDH1A1 | |
| SCHEMBL23628809 | 0.78 | KMT2A (0.53) | KMT2ALMNAMAPK1MEN1ALDH1A1 | |
| SCHEMBL9003427 | 0.78 | ALDH1A1 (0.63) | KMT2ALMNAMAPK1MEN1ALDH1A1 | |
| SCHEMBL3174812 | 0.77 | KMT2A (0.52) | KMT2ALMNAMAPK1MEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3164230 | 0.77 | KMT2A (0.49) | KMT2ALMNAMAPK1MEN1ALDH1A1 | |
| SCHEMBL27045812 | 0.76 | EGLN2 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4590819 | 0.76 | KMT2A (0.56) | KMT2ALMNAMAPK1MEN1ALDH1A1 | |
| SCHEMBL3178473 | 0.76 | KMT2A (0.62) | KMT2ALMNAMAPK1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |