Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069218 | 0.85 | MME (0.62) | MMEACECPA1ACE2 | |
| SCHEMBL4153095 | 0.84 | ITGB3 (0.65) | MMEACEPIN1ITGB3ITGA2B | |
| SCHEMBL4153101 | 0.84 | ITGB3 (0.65) | MMEACEPIN1ITGB3ITGA2B | |
| SCHEMBL5458748 | 0.84 | ITGB3 (0.65) | MMEACEPIN1ITGB3ITGA2B | |
| SCHEMBL24533898 | 0.81 | PIN1 (0.59) | MMEACEPIN1ITGB3ITGA2B | |
| SCHEMBL9069169 | 0.80 | MME (0.66) | MMEACECPA1ACE2 | |
| SCHEMBL5966639 | 0.80 | ITGB3 (0.47) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL5966635 | 0.80 | ITGB3 (0.47) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL9068704 | 0.80 | ACE (0.62) | MMEACECPA1ACE2NAALAD2 | |
| SCHEMBL30468579 | 0.80 | FNTA (0.58) | PIN1ITGB3ITGA2BHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638064-B1 | CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR | SANDOZ AG (AT) | 2021-07-21 | — | — | EP | disclosed |
| US-10106828-B2 | Cell culture medium and process for protein expression, said medium and process comprising a PAM inhibitor | SANDOZ GMBH (AT) | 2018-10-23 | — | — | US | disclosed |
| CN-107629995-A | For the cell culture medium and method of protein expression, the culture medium and method include a kind of PAM inhibitor | 山德士公司 | 2018-01-26 | — | — | CN | disclosed |
| US-20150267238-A1 | Cell Culture Medium And Process For Protein Expression, Said Medium And Process Comprising A Pam Inhibitor | SANDOZ GMBH (AT) | 2015-09-24 | — | — | US | disclosed |
| US-9062337-B2 | Cell culture medium and process for protein expression, said medium and process comprising a PAM inhibitor | SANDOZ GMBH (AT) | 2015-06-23 | — | — | US | disclosed |
| US-20130337506-A1 | CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR | SANDOZ GMBH (AT) | 2013-12-19 | — | — | US | disclosed |
| EP-2638064-A2 | CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR | SANDOZ GMBH (AT) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062810-A2 | CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR | SANDOZ GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |
| EP-2450375-A1 | Cell culture medium and process for protein expression, said medium and process comprising a PAM inhibitor | SANDOZ GMBH (AT) | 2012-05-09 | — | — | EP | disclosed |