SCHEMBL27049353

SCHEMBL27049353

c1ccc(-c2nc(-c3cccc(-c4nc5ccccc5s4)c3)nc(-c3cccc4oc5ccccc5c34)n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.48
▸ POLB P06746 3/20 0.48
▸ ALDH1A1 P00352 3/20 0.48
▸ CTDSP1 Q9GZU7 2/20 0.48
▸ HPGD P15428 2/20 0.48
▸ THRB P10828 2/20 0.48
▸ RAB9A P51151 8/20 0.47
▸ KDM4E B2RXH2 5/20 0.47
▸ NPC1 O15118 5/20 0.47
▸ NFKB1 P19838 4/20 0.47
▸ NFKB2 Q00653 4/20 0.47
▸ RELA Q04206 4/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ LMNA P02545 3/20 0.47
▸ TP53 P04637 2/20 0.47
▸ HSD17B10 Q99714 2/20 0.47
▸ TDP1 Q9NUW8 1/20 0.44
▸ APP P05067 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27049365 0.99 MAPT (0.47) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177310 0.97 MAPT (0.46) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177898 0.95 MAPT (0.44) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177706 0.95 MAPT (0.44) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177365 0.95 MAPT (0.44) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177664 0.95 MAPT (0.46) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177843 0.95 MAPT (0.46) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177371 0.94 MAPT (0.44) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22178252 0.94 MAPT (0.44) MAPTPOLBALDH1A1CTDSP1HPGD
SCHEMBL22177668 0.94 MAPT (0.45) MAPTPOLBALDH1A1CTDSP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 — — US disclosed
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, L3MBTL4, PIEZO1 MAPT 1311/4885POLB 1812/4885ALDH1A1 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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