SCHEMBL2705445

SCHEMBL2705445

Cc1cc(CN2C(=O)C3=C(CCCC3)C2=O)c2c(c1)C(c1ccccc1)C(=O)O2

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 3/20 0.31
GFER P55789 1/20 0.31
ALDH2 P05091 1/20 0.31
TSHR P16473 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2612446 0.82 GAA (0.45) GAAALDH1A1ALDH2
SCHEMBL2612447 0.76 GAA (0.48) GAAALDH1A1GFERSMN1; SMN2
SCHEMBL12352206 0.75 GAA (0.61) GAAKDM4ELMNAALDH1A1GFER
SCHEMBL3119658 0.71 KDM4E (0.43) KDM4ELMNAALDH1A1TSHRSMN1; SMN2
SCHEMBL28910154 0.68 KDM4E (0.40) GAAKDM4ELMNAALDH1A1TSHR
SCHEMBL10135346 0.68 GAA (0.56) GAAKDM4ELMNAALDH1A1GFER
SCHEMBL25724157 0.67 GAA (0.55) GAAKDM4ELMNAALDH1A1GFER
SCHEMBL25723556 0.66 GAA (0.51) GAAKDM4ELMNAALDH1A1TSHR
SCHEMBL272931 0.65 NPC1 (0.49) KDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL29353331 0.65 NPC1 (0.49) KDM4ELMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8274625-B2 Cellulose ester film, method for production of cellulose ester film, and protective film for polarizing plate, polarizing plate and liquid crystal display device each using the cellulose ester film KONICA MINOLTA OPTO, INC. (JP) 2012-09-25 US disclosed
US-8274625-B2 Cellulose ester film, method for production of cellulose ester film, and protective film for polarizing plate, polarizing plate and liquid crystal display device each using the cellulose ester film KONICA MINOLTA OPTO, INC. (JP) 2012-09-25 US disclosed
US-8246737-B2 Cellulose ester optical film, polarizing plate and liquid crystal display using the same, method of manufacturing cellulose ester optical film, and copolymer KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8246737-B2 Cellulose ester optical film, polarizing plate and liquid crystal display using the same, method of manufacturing cellulose ester optical film, and copolymer KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8088831-B2 Cellulose ester film, method for producing cellulose ester film, polarizing plate using the same, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-01-03 US disclosed
US-8088831-B2 Cellulose ester film, method for producing cellulose ester film, polarizing plate using the same, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-01-03 US disclosed
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20100236713-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-09-23 US disclosed
US-20100236713-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-09-23 US disclosed
US-20100188622-A1 CELLULOSE ESTER FILM, METHOD FOR PRODUCTION OF CELLULOSE ESTER FILM, AND PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE EACH USING THE CELLULOSE ESTER FILM KONICA MINOLTA OPTO, INC. (JP) 2010-07-29 US disclosed
US-20100188622-A1 CELLULOSE ESTER FILM, METHOD FOR PRODUCTION OF CELLULOSE ESTER FILM, AND PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE EACH USING THE CELLULOSE ESTER FILM KONICA MINOLTA OPTO, INC. (JP) 2010-07-29 US disclosed
US-20100182548-A1 CELLULOSE ESTER FILM, METHOD FOR PRODUCING CELLULOSE ESTER FILM, POLARIZING PLATE USING THE SAME, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-07-22 US disclosed
US-20100182548-A1 CELLULOSE ESTER FILM, METHOD FOR PRODUCING CELLULOSE ESTER FILM, POLARIZING PLATE USING THE SAME, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-07-22 US disclosed
US-20100069535-A1 Cellulose Ester Optical Film, Polarizing Plate and Liquid Crystal Display Using the Same, Method of Manufacturing Cellulose Ester Optical Film, and Copolymer. KONICA MINOLTA OPTO, INC. (JP) 2010-03-18 US disclosed
US-20100069535-A1 Cellulose Ester Optical Film, Polarizing Plate and Liquid Crystal Display Using the Same, Method of Manufacturing Cellulose Ester Optical Film, and Copolymer. KONICA MINOLTA OPTO, INC. (JP) 2010-03-18 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed