SCHEMBL3119658

SCHEMBL3119658

Cc1cc(CN2C(=O)C3=C(CCCC3)C2=O)c(O)c(-c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 2/20 0.40
PDCD1 Q15116 3/20 0.39
CD274 Q9NZQ7 3/20 0.39
HDAC7 Q8WUI4 2/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
RXFP1 Q9HBX9 1/20 0.34
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28910154 0.80 KDM4E (0.40) KDM4ELMNAMAPTMEN1KMT2A
SCHEMBL30097874 0.80 NPC1 (0.40) KDM4ELMNAMAPTMEN1KMT2A
SCHEMBL2612594 0.79 KDM4E (0.39) KDM4ELMNAMAPTMEN1KMT2A
SCHEMBL29353331 0.77 NPC1 (0.49) KDM4ELMNAMAPTALDH1A1SMN1; SMN2
SCHEMBL272931 0.77 NPC1 (0.49) KDM4ELMNAMAPTALDH1A1SMN1; SMN2
SCHEMBL3088958 0.75 AMY1A (0.45) KDM4ELMNAMAPTMEN1KMT2A
SCHEMBL15498126 0.74 PDCD1 (0.44) PDCD1CD274HDAC7HDAC4HDAC8
SCHEMBL28686539 0.74 RAB9A (0.36) KDM4ELMNAMAPTMEN1KMT2A
SCHEMBL29403943 0.74 NPC1 (0.40) KDM4ELMNAMAPTTSHRALDH1A1
SCHEMBL2538971 0.74 NPC1 (0.40) KDM4ELMNAMAPTTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117916335-A Antireflection film with pressure-sensitive adhesive sheet and image display device 日东电工株式会社 2024-04-19 CN disclosed
CN-117897637-A Optical laminate and image display device 日东电工株式会社 2024-04-16 CN disclosed
CN-117881760-A Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheet, optical laminate, and image display device 日东电工株式会社 2024-04-12 CN disclosed
EP-2154189-A1 Phenol composition and thermoplastic polymer composition comprising the composition Sumitomo Chemical Company, Limited (JP) 2010-02-17 EP disclosed