SCHEMBL272931

SCHEMBL272931

Cc1cc(CN2C(=O)C3=C(CCCC3)C2=O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.49
RAB9A P51151 9/20 0.49
POLB P06746 2/20 0.47
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 7/20 0.38
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 6/20 0.37
MAPT P10636 6/20 0.35
HPGD P15428 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
IGF2BP2 Q9Y6M1 1/20 0.33
THRB P10828 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353331 1.00 NPC1 (0.49) NPC1RAB9APOLBLMNASMN1; SMN2
Oxazole SCHEMBL28947548 0.91 NPC1 (0.41) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL2538971 0.89 NPC1 (0.40) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL29403943 0.89 NPC1 (0.40) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL23222483 0.89 LMNA (0.39) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL30097874 0.89 NPC1 (0.40) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL29388780 0.86 NPC1 (0.53) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL30772443 0.86 NPC1 (0.53) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL674407 0.86 NPC1 (0.53) NPC1RAB9APOLBLMNASMN1; SMN2
SCHEMBL28950900 0.86 NPC1 (0.39) NPC1RAB9APOLBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11976149-B2 Curable composition for optical materials, and optical material TOKUYAMA CORPORATION (JP) 2024-05-07 US claimed
CN-109804008-B Cap or closure made of resin composition comprising polyethylene 道达尔研究技术弗吕公司 2021-03-12 CN claimed
CN-108068561-B Cavity Noise reduction tire 韩国轮胎株式会社 2019-11-26 CN claimed
EP-3448926-B1 CAPS OR CLOSURES MADE FROM A RESIN COMPOSITION COMPRISING POLYETHYLENE TOTAL RES & TECHNOLOGY FELUY (BE) 2019-10-09 EP claimed
US-20190218379-A1 Caps or Closures Made From a Resin Composition Comprising Polyethylene TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2019-07-18 US claimed
EP-3321108-B1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO LTD (KR) 2019-05-15 EP claimed
US-20180134933-A1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO., LTD. (KR) 2018-05-17 US claimed
EP-3321108-A1 TIRE WITH REDUCED CAVITY NOISE Hankook Tire Co., Ltd. (KR) 2018-05-16 EP claimed
WO-2018037122-A1 CAPS OR CLOSURES MADE FROM A RESIN COMPOSITION COMPRISING POLYETHYLENE TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2018-03-01 WO claimed
US-20170329062-A1 OPTICAL FILM AND FLEXIBLE DEVICE USING THE OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-16 US claimed
EP-1291386-B1 RESIN COMPOSITION ZEON CORP (JP) 2008-06-25 EP claimed
US-6953819-B2 Vinyl alicyclic hydrocarbon polymer, especially a hydrogenated vinylaromatic polymer, and a hindered amine type photostabilizer; molded light guide plate ZEON CORPORATION (JP) 2005-10-11 US claimed
US-20030158307-A1 Resin composition ZEON CORPORATION (JP) 2003-08-21 US claimed
EP-1291386-A1 RESIN COMPOSITION ZEON CORPORATION (JP) 2003-03-12 EP claimed
EP-0786675-B1 Spectacle lens TEIJIN CHEMICALS LTD (JP) 2002-11-06 EP claimed
EP-0786675-A2 Spectacle lens Teijin Chemicals, Ltd. (JP) 1997-07-30 EP claimed
US-12637540-B2 Resin produced by polycondensation, and resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-05-26 US disclosed
US-20260140407-A1 ELECTROCHROMIC SHEET AND ELECTROCHROMIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2026-05-21 US disclosed
US-5180764-A Impact strength, high temperature moldability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-01-19 US disclosed
EP-0451539-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260140407-A1 ELECTROCHROMIC SHEET AND ELECTROCHROMIC DEVICE GJB2, LNPK, KCNN2 NPC1 3658/4885RAB9A 3166/4885POLB 2233/4885
US-12637540-B2 Resin produced by polycondensation, and resin composition TAF1, TAF5, PUF60 NPC1 2365/4885RAB9A 4180/4885POLB 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.