⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28846893 | 0.87 | — | — | |
| SCHEMBL1132012 | 0.87 | — | — | |
| Magnesium Chloride Anhydrous SCHEMBL27569410 | 0.87 | — | — | |
| SCHEMBL1998922 | 0.85 | — | — | |
| SCHEMBL16964880 | 0.81 | CYP1A2 (0.31) | — | |
| SCHEMBL98158 | 0.79 | — | — | |
| SCHEMBL8380442 | 0.77 | — | — | |
| SCHEMBL7051483 | 0.73 | — | — | |
| SCHEMBL26702 | 0.73 | — | — | |
| SCHEMBL1394992 | 0.73 | L3MBTL1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6413 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399208-A1 | IRAK INHIBITOR FOR TREATING CYTOKINE RELEASE-RELATED CONDITIONS ASSOCIATED WITH INFECTION BY A RESPIRATORY VIRUS | Rigel Pharmaceuticals, Inc. (US) | 2024-07-17 | — | — | EP | claimed |
| EP-4399206-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | Redona Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | claimed |
| CN-118344342-A | Substituted polyaromatic ring derivatives, compositions and uses thereof | 康迈迪森(北京)医药科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| EP-4395897-A1 | NOVEL RAS INHIBITORS | KHR Biotec GmbH (DE) | 2024-07-10 | — | — | EP | claimed |
| WO-2024141004-A1 | COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND THE USE THEREOF | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2024-07-04 | — | — | WO | claimed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| US-12018014-B2 | Pyrrole-substituted indolone derivative or pharmaceutically acceptable salts thereof, and preparation method therefor and application thereof | SUZHOU GENHOUSE PHARMACEUTICAL CO., LTD. (CN) | 2024-06-25 | — | — | US | claimed |
| CN-118234715-A | Novel RAS inhibitors | KHR生物技术有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118201914-A | 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors | 雷多纳治疗公司 | 2024-06-14 | — | — | CN | claimed |
| WO-2024120467-A1 | PHOSPHORAMIDATE MONOSACCHARIDES, PHARMACEUTICAL COMPOSITIONS, AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | SURIO THERAPEUTICS CO. LTD (CN) | 2024-06-13 | — | — | WO | claimed |
| US-4424222-A | ANTIULCER AND ANTISECRETORY AGENTS | KARL THOMAE GMBH (DE) | 1984-01-03 | — | — | US | claimed |
| US-4410527-A | ANTIULCER AGENTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-10-18 | — | — | US | claimed |
| EP-0086981-A1 | Substituted thienobenzodiazepinones, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-08-31 | — | — | EP | claimed |
| EP-0086980-A1 | Substituted dibenzodiazepinones, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-08-31 | — | — | EP | claimed |
| EP-0085893-A2 | Pyridobenzodiazepinones, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1983-08-17 | — | — | EP | claimed |
| US-4182776-A | Method of treating lipidemia with aryloxyalkylaminobenzoic acids and esters | AMERICAN CYANAMID COMPANY (US) | 1980-01-08 | — | — | US | claimed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |
| US-3974284-A | 1,1A,6,10B-Tetrahydro-1,6-methano-dibenzo[a,e]cyclopropa[c]cycloheptenes as antidepressants | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | claimed |
| US-3968143-A | Phenoxypropionic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-07-06 | — | — | US | claimed |
| US-3956334-A | CHOLESTEROL AND TRIGLYCERIDE LOWERING ACTIVITY IN BLOOD | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-05-11 | — | — | US | claimed |