Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18804001 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL10551777 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL29726945 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL11069629 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL4524706 | 1.00 | — | — | |
| SCHEMBL2481345 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL9717348 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL1524410 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL1141520 | 0.97 | — | — | |
| SCHEMBL1524228 | 0.89 | TSHR (0.42) | ALDH1A1LMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407726-B2 | Using stereoretention for the stereoselective formation of e-macrocycles with Ru-based olefin metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-08-09 | — | — | US | disclosed |
| US-20200385360-A1 | USING STEREORETENTION FOR THE STEREOSELECTIVE FORMATION OF E-MACROCYCLES WITH RU-BASED OLEFIN METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-12-10 | — | — | US | disclosed |
| US-8088791-B2 | Antibacterial agents | Biots Scientific Management Pty Ltd (AU) | 2012-01-03 | — | — | US | disclosed |
| US-20100173933-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2010-07-08 | — | — | US | disclosed |
| US-4784796-A | REACTION OF UNSATURATED ALDEHYDE WITH DIAMINE, FURTHER REACTED WITH CARBOXYLIC ACID OR QUATERNIZATION | THE DOW CHEMICAL COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| US-4784797-A | ALDEHYDE REACTED WITH DIAMINE FOLLOWED BY SALT FORMATION OR QUATERNIZATION | THE DOW CHEMICAL COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385360-A1 | USING STEREORETENTION FOR THE STEREOSELECTIVE FORMATION OF E-MACROCYCLES WITH RU-BASED OLEFIN METATHESIS CATALYSTS | OXER1, SPR, DHCR7 | ALDH1A1 1159/4885LMNA 4870/4885HSD17B10 117/4885 |
| US-11407726-B2 | Using stereoretention for the stereoselective formation of e-macrocycles with Ru-based olefin metathesis catalysts | OXER1, SPR, DHCR7 | ALDH1A1 1159/4885LMNA 4870/4885HSD17B10 117/4885 |
| US-20100173933-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | ALDH1A1 800/4885LMNA 1817/4885HSD17B10 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.