SCHEMBL2705980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL204212	0.85	PPARG (0.47)	LMNAHTTPPARGRAB9APARP1
	SCHEMBL19285699	0.84	KDM1A (0.50)	LMNAHTTPARP1NPC1MAPT
	SCHEMBL2705646	0.83	SIRT2 (0.49)	LMNAHTTMRGPRX4SPHK2SPHK1
	SCHEMBL2705638	0.82	LMNA (0.48)	LMNAHTTPARP1MRGPRX4
	SCHEMBL202627	0.82	MAOB (0.56)	LMNAHTTMRGPRX4MAOBPARP10
	SCHEMBL2707206	0.82	FFAR1 (0.51)	LMNAHTTMRGPRX4MAOBPARP10
	SCHEMBL203855	0.82	MRGPRX4 (0.43)	LMNAHTTPARP1MRGPRX4
	SCHEMBL2704584	0.81	MRGPRX4 (0.48)	LMNAHTTMRGPRX4
	SCHEMBL2707335	0.81	MRGPRX4 (0.54)	MRGPRX4MAOB
	SCHEMBL2705640	0.81	MRGPRX4 (0.52)	LMNAHTTRAB9ANPC1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.