Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | CDK9 | P50750 | 4/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 5/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9881936 | 0.83 | PRKCA (0.64) | PIM1PIM3PIM2PRKCAPRKCQ | |
| SCHEMBL1834932 | 0.81 | PRKCQ (0.49) | ALDH1A1PIM1PIM3PIM2PRKCA | |
| SCHEMBL17525868 | 0.80 | PIM1 (0.53) | PIM1PIM3PIM2PRKCAPRKCQ | |
| SCHEMBL9881926 | 0.79 | PIM1 (0.65) | PIM1PIM3PIM2PRKCAPRKCQ | |
| SCHEMBL27062792 | 0.78 | CDK2 (0.82) | CCNT1CCNA2CDK2CDK9RET | |
| SCHEMBL9882039 | 0.78 | PRKCQ (0.52) | PIM1PIM3PIM2ADRB1PRKCA | |
| SCHEMBL9881930 | 0.75 | PRKCQ (0.54) | ALDH1A1KDM4EPIM1PIM3PIM2 | |
| SCHEMBL8939690 | 0.74 | CDK2 (0.83) | CCNT1CCNA2CDK2CDK9RET | |
| SCHEMBL9882374 | 0.74 | PRKCQ (0.48) | PIM1PIM3PIM2PRKCAPRKCQ | |
| SCHEMBL9882040 | 0.74 | PRKD1 (0.53) | PIM1PIM3PIM2ADRB1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310081-A1 | CTLA-4 SMALL MOLECULE DEGRADATION AGENT AND APPLICATION THEREOF | Suzhou Guokuang Pharmtech. Co., Ltd. (CN) | 2024-01-24 | — | — | EP | disclosed |