Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 18/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 8/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9881936 | 0.87 | PRKCA (0.64) | PIM1PIM3PIM2PRKCQPRKCD | |
| SCHEMBL9882039 | 0.84 | PRKCQ (0.52) | PIM1PIM3PIM2PRKCQPRKCD | |
| SCHEMBL9881926 | 0.83 | PIM1 (0.65) | PIM1PIM3PIM2PRKCQPRKCD | |
| SCHEMBL17525840 | 0.83 | PRKCQ (0.58) | PIM1PIM3PIM2PRKCQPRKCD | |
| SCHEMBL8509439 | 0.80 | PRKCQ (0.59) | PIM1PRKCQPRKCDPRKCA | |
| SCHEMBL8509447 | 0.80 | PRKCQ (0.59) | PIM1PRKCQPRKCDPRKCA | |
| SCHEMBL9882040 | 0.80 | PRKD1 (0.53) | PIM1PIM3PIM2PRKCQPRKCD | |
| SCHEMBL9882374 | 0.80 | PRKCQ (0.48) | PIM1PIM3PIM2PRKCQPRKCD | |
| SCHEMBL1834932 | 0.80 | PRKCQ (0.49) | PIM1PIM3PIM2PRKCQPRKCD | |
| SCHEMBL27062796 | 0.80 | CCNT1 (0.51) | PIM1PIM3PIM2PRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318408-B1 | TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS | VERTEX PHARMA (US) | 2016-02-17 | — | — | EP | disclosed |