SCHEMBL27064508

SCHEMBL27064508

CSCCOc1cc(CCCCCC(=O)C(C)C)ccc1F

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 4/20 0.35
▸ ALB P02768 1/20 0.35
▸ CYP4F2 P78329 1/20 0.34
▸ CYP4A11 Q02928 1/20 0.34
▸ CYSLTR2 Q9NS75 1/20 0.34
▸ CYSLTR1 Q9Y271 1/20 0.34
▸ PPARG P37231 1/20 0.34
▸ PPARA Q07869 1/20 0.34
▸ BIRC5 O15392 1/20 0.33
▸ ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25122727 0.85 PPARG (0.40) CYP4F2CYP4A11PPARGPPARA
SCHEMBL23845279 0.84 CYP4F2 (0.37) CYP4F2CYP4A11PPARGPPARA
SCHEMBL27064513 0.81 CNR2 (0.41) —
SCHEMBL29307149 0.76 CYP4F2 (0.36) CYP4F2CYP4A11PPARGPPARAALOX5
SCHEMBL26224388 0.74 CYP1A2 (0.41) CYP4F2CYP4A11PPARGPPARAALOX5
SCHEMBL22526055 0.73 CYP4F2 (0.41) CYP4F2CYP4A11PPARGPPARA
SCHEMBL25122669 0.72 BCHE (0.41) PPARGPPARAALOX5
SCHEMBL16981025 0.71 CYP4F2 (0.43) TTRALBCYP4F2CYP4A11
SCHEMBL23475823 0.71 FAAH (0.46) —
SCHEMBL23842320 0.71 PPARG (0.40) PPARGPPARAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025878-A1 MDM2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025878-A1 MDM2 DEGRADERS AND USES THEREOF MDM2, TP53, MDM4 TTR 2894/4885ALB 2586/4885CYP4F2 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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