Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526055 | 0.88 | CYP4F2 (0.41) | CYP4F2CYP4A11PPARGPPARAKCNH2 | |
| SCHEMBL23845279 | 0.87 | CYP4F2 (0.37) | CYP4F2CYP4A11PPARGPPARAKCNH2 | |
| SCHEMBL29307148 | 0.86 | TSHR (0.37) | PPARGPPARAALOX5 | |
| SCHEMBL22525834 | 0.81 | FUT7 (0.38) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL27064508 | 0.76 | TTR (0.35) | CYP4F2CYP4A11PPARGPPARAALOX5 | |
| SCHEMBL25122727 | 0.76 | PPARG (0.40) | CYP4F2CYP4A11PPARGPPARA | |
| SCHEMBL26206475 | 0.74 | S1PR2 (0.37) | PPARGPPARAALOX5 | |
| SCHEMBL20188093 | 0.74 | CYP4F2 (0.39) | CYP4F2CYP4A11KCNH2TMEM97SIGMAR1 | |
| SCHEMBL26224388 | 0.74 | CYP1A2 (0.41) | CYP4F2CYP4A11PPARGPPARAALOX5 | |
| SCHEMBL22525838 | 0.73 | TSHR (0.39) | PPARGPPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148060-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |