SCHEMBL2707256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3704134	1.00	NPC1 (0.44)	NPC1RAB9AL3MBTL1GLASMPD1
	SCHEMBL201245	0.81	SMPD1 (0.54)	NPC1RAB9AL3MBTL1SMPD1SMN1; SMN2
	SCHEMBL201043	0.76	MAPT (0.51)	NPC1RAB9AL3MBTL1GLASMPD1
	SCHEMBL2705648	0.75	NPC1 (0.44)	NPC1RAB9AL3MBTL1SMPD1SMN1; SMN2
	SCHEMBL2706612	0.75	KDM4E (0.43)	L3MBTL1SMPD1
	SCHEMBL2318034	0.73	MAPT (0.39)	NPC1RAB9AL3MBTL1SMPD1CASP3
	SCHEMBL203129	0.73	MAPT (0.53)	NPC1RAB9AL3MBTL1CASP3SENP7
	SCHEMBL19285699	0.73	KDM1A (0.50)	NPC1L3MBTL1MAPT
	SCHEMBL2706027	0.72	L3MBTL1 (0.58)	NPC1RAB9AL3MBTL1SMPD1ALOX5
	SCHEMBL201638	0.72	FFAR1 (0.42)	NPC1RAB9AL3MBTL1SMPD1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.