Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Thymopentin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.60 |
| ▸ | NPY1R | P25929 | 8/20 | 0.60 |
| ▸ | NPY2R | P49146 | 6/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.60 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.51 |
| ▸ | TFPI | P10646 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | VIPR2 | P41587 | 2/20 | 0.49 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thymopentin SCHEMBL29512423 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| SCHEMBL30331711 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| Thymopentin SCHEMBL989519 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| Thymopentin SCHEMBL7498758 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| Thymopentin SCHEMBL44001 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| Thymopentin SCHEMBL29512388 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| Thymopentin SCHEMBL29512397 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| SCHEMBL29611531 | 0.96 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| Acetic Acid SCHEMBL6940231 | 0.95 | NPY4R (0.67) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| SCHEMBL30918767 | 0.95 | NPY4R (0.57) | NPY4RNPY1RNPY2RNPY5RIL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10946141-B2 | Sterile protective cover comprising a device for opthalmic delivery | VIRCHOW BIOTECH PVT. LTD. (IN) | 2021-03-16 | — | — | US | disclosed |
| EP-2505189-B1 | Stabilizing alkylglycoside compositions and method thereof | AEGIS THERAPEUTICS LLC (US) | 2018-08-08 | — | — | EP | disclosed |
| US-20180140461-A1 | STERILE PROTECTIVE COVER COMPRISING A DEVICE FOR OPTHALMIC DELIVERY | VIRCHOW BIOTECH PVT. LTD. (IN) | 2018-05-24 | — | — | US | disclosed |
| US-20180092770-A1 | STERILE PROTECTIVE COVER COMPRISING A DEVICE FOR OPTHALMIC DELIVERY | VIRCHOW BIOTECH INC. | 2018-04-05 | — | — | US | disclosed |
| US-20170258633-A1 | NOVEL DEVICE FOR OPHTHALMIC DELIVERY | VIRCHOW BIOTECH PVT. LTD. (IN) | 2017-09-14 | — | — | US | disclosed |
| US-20170239335-A1 | STABLE INJECTABLE COMPOSITION OF PHARMACEUTICALLY ACTIVE AGENTS AND PROCESS FOR ITS PREPARATION | PIRAMAL ENTPR LTD (IN) | 2017-08-24 | — | — | US | disclosed |
| EP-3206706-A1 | STABLE INJECTABLE COMPOSITION OF PHARMACEUTICALLY ACTIVE AGENTS AND PROCESS FOR ITS PREPARATION | Piramal Enterprises Limited (IN) | 2017-08-23 | — | — | EP | disclosed |
| US-20170216397-A1 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF | AEGIS THERAPEUTICS, LLC | 2017-08-03 | — | — | US | disclosed |
| EP-2303237-B1 | PREPARATION METHOD OF BIODEGRADABLE MICRO-PARTICLES CONTAINING DRUGS | UNIV ARKANSAS (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9446134-B2 | Stabilizing alkylglycoside compositions and methods thereof | AEGIS THERAPEUTICS, LLC (US) | 2016-09-20 | — | — | US | disclosed |
| US-7390788-B2 | Pharmaceutically active peptide T composition comprising non-aggregated D-ala1-Peptide T-amide, produced by suspending the D-ala1-Peptide T-amide in 80% trifluoroethanol for 24 hours at 37 C with shaking, removing trifluoroethanol, and suspending the D-ala1-Peptide T-amide in aqueous solution | PEPTIDE ACCOUNT LLC | 2008-06-24 | — | — | US | disclosed |
| US-20070298010-A1 | Stabilizing alkylglycoside compositions and methods thereof | AEGIS THERAPEUTICS LLC (US) | 2007-12-27 | — | — | US | disclosed |
| WO-2007149096-A1 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF | AEGIS THERAPEUTICS, INC. (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20070111938-A1 | Peptide pharmaceutical compositions | RAPID PHARMACEUTICALS, LLC (US) | 2007-05-17 | — | — | US | disclosed |
| WO-2007002465-A2 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF | RAPID PHARMACEUTICALS, LLC (US) | 2007-01-04 | — | — | WO | disclosed |
| EP-0391218-B1 | Agent for the atopy prophylaxis | BEIERSDORF AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| EP-0324659-B1 | Enzymatic process for producing immunomodulating pentapeptides and intermediates for use in the process | CARLBIOTECH LTD AS (DK) | 1995-08-02 | — | — | EP | disclosed |
| EP-0391218-A2 | Agent for the atopy prophylaxis | Beiersdorf Aktiengesellschaft (DE) | 1990-10-10 | — | — | EP | disclosed |
| WO-1989006656-A1 | ENZYMATIC PROCESS FOR PRODUCING IMMUNOMODULATING PENTAPEPTIDES AND INTERMEDIATES FOR USE IN THE PROCESS | CARLSBERG BIOTECHNOLOGY LTD. A/S (DK) | 1989-07-27 | — | — | WO | disclosed |
| EP-0324659-A2 | Enzymatic process for producing immunomodulating pentapeptides and intermediates for use in the process | CARLBIOTECH LTD. A/S (DK) | 1989-07-19 | — | — | EP | disclosed |