Thymopentin

Thymopentin

SCHEMBL44001

CC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 13/20 0.62
NPY1R P25929 8/20 0.62
NPY2R P49146 6/20 0.62
NPY5R Q15761 5/20 0.62
IL23R Q5VWK5 2/20 0.51
TFPI P10646 1/20 0.50
VIPR2 P41587 2/20 0.50
OPRD1 P41143 1/20 0.49
VIPR1 P32241 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymopentin SCHEMBL989519 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL29512397 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL7498758 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL29512388 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL29512423 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL30331711 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL270731 0.98 NPY4R (0.60) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL29611531 0.98 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL29512422 0.96 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL30918783 0.95 NPY4R (0.69) NPY4RNPY1RNPY2RNPY5RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6910 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 US claimed
EP-4735581-A2 METHODS OF MAKING AND USING ENGINEERED IMMUNE CELLS The Regents of University of California (US) 2026-05-06 EP claimed
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 EP claimed
EP-4704867-A1 METHODS OF DOSING AND ADMINISTRATION OF ENGINEERED ISLET CELLS Sana Biotechnology, Inc. (US) 2026-03-11 EP claimed
US-20260048086-A1 METHODS OF DOSING AND ADMINISTRATION OF ENGINEERED ISLET CELLS SANA BIOTECHNOLOGY INC (US) 2026-02-19 US claimed
US-12533321-B2 Polypeptide formulations for oral delivery Bhami's Research Laboratory, Pvt. Ltd. (IN) 2026-01-27 US claimed
EP-4642761-A1 BIOREACTIVE PROTEINS CONTAINING AN UNNATURAL AMINO ACID AND ARGININE The Regents of University of California (US) 2025-11-05 EP claimed
US-12459989-B2 Antibody therapies for human immunodeficiency virus (HIV) BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2025-11-04 US claimed
US-20250325680-A1 HIGH-PERMEABILITY PROTEIN OR POLYPEPTIDE CONJUGATE AND USE THEREOF Hangzhou Tito Biotechnology Partnership Enterprise ( Limited Partnership ) (CN) 2025-10-23 US claimed
EP-4631514-A1 ORAL POLYPEPTIDE COMPOSITION AND USE THEREOF Hefei Tianhui Biotech Co., Ltd. (CN) 2025-10-15 EP claimed
EP-0420649-A2 Stabilized aqueous formulations of small peptides IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1991-04-03 EP claimed
EP-0406931-A2 New analogues of all-bond retroinverted thymopentin, the method for the synthesis of the same and their employment for the preparation of pharmaceutical compositions SCLAVO S.p.A. (IT) 1991-01-09 EP claimed
EP-0393786-A1 New retro-inverse, one- or more bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical SCLAVO S.p.A. (IT) 1990-10-24 EP claimed
WO-1990012029-A1 LYOPHILIZED PEPTIDE FORMULATIONS IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1990-10-18 WO claimed
WO-1990007933-A1 COMPOSITIONS CONTAINING THYMOPENTIN FOR TOPICAL TREATMENT OF SKIN DISORDERS IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1990-07-26 WO claimed
EP-0378413-A2 Compositions for topical treatment of skin disorders IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1990-07-18 EP claimed
WO-1989009229-A1 TREATMENT OF HIV VIREMIC PATIENTS WITH THYMOPENTIN IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1989-10-05 WO claimed
EP-0335726-A2 Use of thymopentin and derivatives in treatment of HIV viremic patients IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1989-10-04 EP claimed
US-4749690-A ADMINISTERING OLIGOPEPTIDE ORTHO PHARMACEUTICAL CORPORATION (US) 1988-06-07 US claimed
EP-0235904-A2 Treatment of allergy with thymopentin ORTHO PHARMACEUTICAL CORPORATION (US) 1987-09-09 EP claimed