Thymopentin

Thymopentin

SCHEMBL989519

CC(C)C(NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(N)CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 13/20 0.62
NPY1R P25929 8/20 0.62
NPY2R P49146 6/20 0.62
NPY5R Q15761 5/20 0.62
IL23R Q5VWK5 2/20 0.51
TFPI P10646 1/20 0.50
VIPR2 P41587 2/20 0.50
OPRD1 P41143 1/20 0.49
VIPR1 P32241 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymopentin SCHEMBL29512397 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL44001 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL7498758 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL29512388 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL29512423 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL30331711 1.00 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5RIL23R
Thymopentin SCHEMBL270731 0.98 NPY4R (0.60) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL29611531 0.98 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL29512422 0.96 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL30918783 0.95 NPY4R (0.69) NPY4RNPY1RNPY2RNPY5RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1714861-B Thymus penta peptide slow releasing micro ball and its preparing method INST MATERIA MEDICA CAMS 2012-10-10 CN claimed
CN-109836455-B Liquid phase synthesis method of thymopentin based on phosphorus or phosphorus acyloxy diphenyl methanol and derivatives thereof and assistance 西北工业大学 2021-11-16 CN disclosed
CN-105125451-A Composition capable of inhibiting hair growth and preparation method thereof LIN TONG 2015-12-09 CN disclosed
CN-105106932-A Hair regrowth composition and preparation method thereof LIN TONG 2015-12-02 CN disclosed
CN-103536898-B Thymopentin (TP-5) drug composition CHENGDU TIANTAISHAN PHARMACEUTICAL CO LTD 2015-06-17 CN disclosed
CN-103536567-B Thymopentin (TP-5) powder injection CHENGDU TIANTAISHAN PHARMACEUTICAL CO LTD 2015-03-25 CN disclosed
US-8822542-B2 Isoketal scavengers and mitigation of disorders involving oxidative injury VANDERBILT UNIVERSITY (US) 2014-09-02 US disclosed
CN-103536567-A Thymopentin (TP-5) powder injection CHENGDU TIANTAISHAN PHARMACEUTICAL CO LTD 2014-01-29 CN disclosed
CN-103536898-A Thymopentin (TP-5) drug composition CHENGDU TIANTAISHAN PHARMACEUTICAL CO LTD 2014-01-29 CN disclosed
EP-2477594-A1 ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY Vanderbilt University (US) 2012-07-25 EP disclosed
US-20120157501-A1 ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY VANDERBILT UNIVERSITY 2012-06-21 US disclosed
WO-2011008202-A1 ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY VANDERBILT UNIVERSITY (US) 2011-01-20 WO disclosed
US-7705054-B1 Method of preventing and/or treating oxidant injury in neurodegenerative and oxidative diseases VANDERBILT UNIVERSITY (US) 2010-04-27 US disclosed
US-6677161-B2 Aerogels and other coatings as collection media and matrix supports for MALDI-MS applications VERIDIAN ERIM INTERNATIONAL, INC. 2004-01-13 US disclosed
US-20020081746-A1 Aerogels and other coatings as collection media and matrix supports for MALDI-MS applications VERIDIAN ERIM INTERNATIONAL, INC. 2002-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157501-A1 ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY PDXK, KYNU, FN3K NPY4R 964/4885NPY1R 1244/4885NPY2R 1375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.