Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092151 | 0.88 | NR1H4 (0.44) | CDK9PLAUNR1H4KDM4EHPGD | |
| SCHEMBL31193423 | 0.86 | CDK9 (0.76) | CDK9PLAUSALL4BRD4GAA | |
| SCHEMBL27075694 | 0.86 | CDK9 (0.61) | CDK9SALL4BRD4GAATP53 | |
| SCHEMBL20889542 | 0.84 | SALL4 (0.55) | CDK9PLAUSALL4BRD4GAA | |
| SCHEMBL31193286 | 0.83 | CDK9 (0.55) | CDK9PLAUSALL4BRD4GAA | |
| SCHEMBL27075692 | 0.82 | GAA (0.55) | GAATP53MAPTKDM4EHPGD | |
| SCHEMBL20889554 | 0.81 | CDK9 (0.53) | CDK9PLAUSALL4BRD4GAA | |
| SCHEMBL20889552 | 0.77 | SALL4 (0.81) | CDK9PLAUSALL4BRD4GAA | |
| SCHEMBL27075693 | 0.75 | CDK9 (0.49) | CDK9SALL4BRD4GAATP53 | |
| SCHEMBL27104987 | 0.74 | CDK9 (0.57) | CDK9SALL4BRD4GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891396-B1 | 5-substituted pyrido[3″,4″:4′,5′]pyrrolo[3′,2′:4,5]imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891396-B1 | 5-substituted pyrido[3″,4″:4′,5′]pyrrolo[3′,2′:4,5]imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | CSNK2A1, CSNK2A2, CSNK2A3 | CDK9 87/4885PLAU 4083/4885SALL4 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.