Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181810 | 0.75 | PDE5A (0.43) | L3MBTL1KMT2AIDO1TDO2POLB | |
| SCHEMBL12171669 | 0.62 | FAAH (0.39) | L3MBTL1KMT2AIDO1TDO2POLB | |
| SCHEMBL182540 | 0.61 | MEN1 (0.45) | KMT2APOLBMEN1MAPTTP53 | |
| SCHEMBL22349773 | 0.60 | DHODH (0.44) | L3MBTL1KMT2AIDO1TDO2POLB | |
| SCHEMBL17177053 | 0.59 | KMT2A (0.56) | L3MBTL1KMT2APOLBRECQLTDP1 | |
| SCHEMBL31420309 | 0.59 | GAA (0.55) | L3MBTL1KMT2AIDO1TDO2POLB | |
| SCHEMBL30474531 | 0.59 | L3MBTL1 (0.59) | L3MBTL1KMT2APOLBRECQLTDP1 | |
| SCHEMBL16554846 | 0.59 | L3MBTL1 (0.59) | L3MBTL1KMT2APOLBRECQLTDP1 | |
| SCHEMBL3011187 | 0.59 | GAA (0.55) | L3MBTL1KMT2AIDO1TDO2POLB | |
| SCHEMBL21935952 | 0.59 | MEN1 (0.69) | L3MBTL1KMT2APOLBRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387995-A1 | Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith | PTC Therapeutics, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |