SCHEMBL2707945

SCHEMBL2707945

C=C(C)C(=O)OC.Oc1cccc(C=CC=Cc2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.50
CDK1 P06493 1/20 0.50
CDK4 P11802 1/20 0.50
CCNB1 P14635 1/20 0.50
CCND1 P24385 1/20 0.50
CCNB3 Q8WWL7 1/20 0.50
MMP1 P03956 9/20 0.48
MMP2 P08253 9/20 0.48
MMP9 P14780 9/20 0.48
LMNA P02545 1/20 0.45
P4HB P07237 1/20 0.44
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
CYP19A1 P11511 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ABL1 P00519 1/20 0.43
BCR P11274 1/20 0.43
HSP90AA1 P07900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708790 0.89 ABCG2 (0.49) MMP1MMP2MMP9LMNAMAOA
SCHEMBL2708850 0.85 CCNB2 (0.47) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL2707793 0.85 LMNA (0.48) CCNB2CDK1CDK4CCNB1CCND1
(Z)-1,2-Diphenylethene SCHEMBL5875864 0.83 ALDH1A1 (0.56) LMNACYP2C9CYP2C19
(Z)-1,2-Diphenylethene SCHEMBL5875859 0.83 ALDH1A1 (0.56) LMNACYP2C9CYP2C19
Juarezic Acid SCHEMBL5162270 0.83 HDAC3 (0.51) LMNAMAOAMAOB
SCHEMBL179884 0.83 LMNA (0.47) LMNAMAOB
SCHEMBL11232759 0.82 LMNA (0.49) LMNAMAOBCYP2C19
SCHEMBL27462680 0.82 LMNA (0.49) LMNAMAOBCYP2C19
SCHEMBL10591788 0.82 LMNA (0.46) LMNAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2447291-B1 HIGH-MOLECULAR-WEIGHT COPOLYMER NIPPON SODA CO (JP) 2015-04-08 EP disclosed
US-8729187-B2 High-molecular-weight copolymer NIPPON SODA CO., LTD. (JP) 2014-05-20 US disclosed
US-20120123076-A1 HIGH-MOLECULAR-WEIGHT COPOLYMER NIPPON SODA CO., LTD (JP) 2012-05-17 US disclosed
EP-2447291-A1 HIGH-MOLECULAR-WEIGHT COPOLYMER Nippon Soda Co., Ltd. (JP) 2012-05-02 EP disclosed