Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 13/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23725965 | 1.00 | CD274 (0.36) | CD274PDCD1KCNA5NTRK1PDCD1LG2 | |
| SCHEMBL25688688 | 0.87 | PDCD1 (0.37) | CD274PDCD1MAPK1IRAK4 | |
| SCHEMBL27081739 | 0.84 | CD274 (0.42) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27081733 | 0.84 | CD274 (0.42) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27080877 | 0.81 | PRMT5 (0.35) | KCNA5 | |
| SCHEMBL27080703 | 0.81 | PRMT5 (0.35) | KCNA5 | |
| SCHEMBL29983679 | 0.78 | CD274 (0.43) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23724879 | 0.78 | CD274 (0.43) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23724875 | 0.78 | CD274 (0.43) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23725969 | 0.77 | CD274 (0.36) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313968-A2 | SUBSTITUTED 1-ARYL-1'-HETEROARYL COMPOUNDS, SUBSTITUTED 1,1'-BIHETEROARYL COMPOUNDS, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2024-02-07 | — | — | EP | disclosed |