SCHEMBL27082415

SCHEMBL27082415

O=C(O)CCC(=O)NNC(=O)c1cccs1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
KMT2A Q03164 4/20 0.74
CYP2C19 P33261 2/20 0.74
MEN1 O00255 2/20 0.74
CYP2C9 P11712 1/20 0.74
RAB9A P51151 3/20 0.61
SMN1; SMN2 Q16637 1/20 0.60
HTT P42858 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.57
MAPT P10636 1/20 0.56
APEX1 P27695 1/20 0.54
ELANE P08246 1/20 0.53
HDAC1 Q13547 1/20 0.53
NPC1 O15118 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1862342 0.84 ALDH1A1 (0.72) ALDH1A1KMT2ACYP2C19MEN1CYP2C9
SCHEMBL1858111 0.82 RAB9A (0.78) ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL27921512 0.80 CYP2C19 (0.69) ALDH1A1KMT2ACYP2C19MEN1CYP2C9
SCHEMBL6771140 0.80 ALDH1A1 (0.67) ALDH1A1KMT2ACYP2C19MEN1CYP2C9
SCHEMBL4739925 0.79 RAB9A (0.73) ALDH1A1KMT2ACYP2C19MEN1CYP2C9
SCHEMBL12666936 0.79 HDAC1 (0.68) ALDH1A1KMT2ACYP2C19MEN1CYP2C9
SCHEMBL1866588 0.79 ALDH1A1 (0.65) ALDH1A1KMT2ACYP2C19MEN1CYP2C9
SCHEMBL12629976 0.79 HDAC1 (0.68) ALDH1A1KMT2ACYP2C19MEN1CYP2C9
SCHEMBL9466891 0.77 HPGD (0.63) ALDH1A1KMT2ACYP2C19MEN1RAB9A
SCHEMBL12491240 0.77 KDM4E (0.72) ALDH1A1CYP2C19CYP2C9RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199803-A1 Polycarbonate Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-20 US disclosed
EP-4317318-A1 POLYCARBONATE RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2024-02-07 EP disclosed
CN-116507671-A Polycarbonate resin composition 旭化成株式会社 2023-07-28 CN disclosed
WO-2022209725-A1 POLYCARBONATE RESIN COMPOSITION 旭化成株式会社 2022-10-06 WO disclosed