SCHEMBL27083170

SCHEMBL27083170

Nc1c(C(F)(F)F)cc(C(F)(F)F)c(C(F)(F)F)c1C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KIF11 P52732 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
MAPT P10636 2/20 0.31
BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25780819 0.84 GAA (0.41) GAAGLAPOLBTSHRKDM4E
SCHEMBL13385821 0.83 CA2 (0.39) GAAGLAPOLBTSHRKDM4E
SCHEMBL29620303 0.83 CA2 (0.39) GAAGLAPOLBTSHRKDM4E
SCHEMBL29725319 0.83 CA12 (0.39) GAAGLAPOLBTSHRKDM4E
SCHEMBL23416481 0.81 GAA (0.35) GAAGLAPOLBTSHRALDH1A1
SCHEMBL5507098 0.79 GLA (0.34) GAAGLAPOLBTSHRKDM4E
SCHEMBL5522959 0.79 GLA (0.34) GAAGLAPOLBTSHRKDM4E
SCHEMBL7875176 0.78 GLA (0.33) GAAGLAPOLBTSHRADRB2
SCHEMBL7875189 0.76 GLA (0.32) GAAGLAPOLBTSHR
SCHEMBL8993265 0.76 TSHR (0.42) GAAGLAPOLBTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199810-A1 METHOD FOR PRODUCING POLYIMIDE RESIN POWDER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-06-20 US disclosed
EP-4317254-A1 METHOD FOR PRODUCING POLYIMIDE RESIN POWDER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-02-07 EP disclosed
WO-2022202150-A1 METHOD FOR PRODUCING POLYIMIDE RESIN POWDER 三菱瓦斯化学株式会社 2022-09-29 WO disclosed