Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922243 | 0.88 | GLA (0.35) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL28945538 | 0.86 | KIF11 (0.60) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL28674664 | 0.86 | KIF11 (0.46) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL5669382 | 0.83 | HSD17B1 (0.36) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL5987423 | 0.82 | KDM4E (0.33) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL11844970 | 0.82 | GAA (0.54) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL17563226 | 0.81 | KIF11 (0.37) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL394903 | 0.80 | TSHR (0.41) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL14601908 | 0.78 | SMN1; SMN2 (0.45) | TSHRGLAPOLBGAAKIF11 | |
| SCHEMBL10215552 | 0.76 | ACHE (0.45) | GAAKIF11ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450926-B1 | Fluorine-containing polyimides and precursors thereof | HITACHI CHEMICAL CO LTD (JP) | 1996-07-31 | — | — | EP | disclosed |
| EP-0450926-A2 | Fluorine-containing polyimides and precursors thereof | Hitachi Chemical Co., Ltd. (JP) | 1991-10-09 | — | — | EP | disclosed |