Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824036 | 0.83 | TSHR (0.40) | TSHRTDP1ALDH1A1 | |
| SCHEMBL14479303 | 0.80 | CYP2D6 (0.45) | — | |
| SCHEMBL987062 | 0.78 | ALDH1A1 (0.39) | TSHRTDP1ALDH1A1 | |
| SCHEMBL2762967 | 0.78 | ALDH1A1 (0.39) | TSHRTDP1ALDH1A1 | |
| SCHEMBL11409761 | 0.78 | TSHR (0.44) | TSHRTDP1ALDH1A1 | |
| SCHEMBL29222451 | 0.76 | FDPS (0.31) | — | |
| SCHEMBL12515790 | 0.76 | — | — | |
| SCHEMBL13827405 | 0.76 | — | — | |
| SCHEMBL10794688 | 0.75 | TSHR (0.46) | TSHRTDP1ALDH1A1 | |
| SCHEMBL23931 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445951-A1 | SILICONE HYDROGELS FORMED FROM SYMMETRIC HYDROXYL FUNCTIONALIZED SILOXANES | Johnson & Johnson Vision Care, Inc. (US) | 2012-05-02 | — | — | EP | disclosed |
| US-20100331443-A1 | SILICONE HYDROGELS FORMED FROM SYMMETRIC HYDROXYL FUNCTIONALIZED SILOXANES | JOHNSON & JOHNSON VISION CARE, INC. | 2010-12-30 | — | — | US | disclosed |
| WO-2010151411-A1 | SILICONE HYDROGELS FORMED FROM SYMMETRIC HYDROXYL FUNCTIONALIZED SILOXANES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010039611-A1 | PROCESS FOR FORMING SILICONE HYDROGEL ARTICLES HAVING IMPROVED OPTICAL PROPERTIES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-04-08 | — | — | WO | disclosed |