Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 3/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002174 | 0.90 | GPR119 (0.44) | GPR119KCNH2CYP3A4NPC1RAB9A | |
| SCHEMBL24437753 | 0.84 | GPR119 (0.51) | GPR119KCNH2CYP3A4NPC1RAB9A | |
| SCHEMBL27086530 | 0.84 | GPR119 (0.43) | GPR119KCNH2CYP3A4KITAOC3 | |
| SCHEMBL11957018 | 0.84 | GPR119 (0.46) | GPR119NPC1RAB9AKDM4EPDE8B | |
| SCHEMBL21791392 | 0.83 | GPR119 (0.45) | GPR119KCNH2CYP3A4NPC1RAB9A | |
| SCHEMBL17411217 | 0.79 | GPR119 (0.47) | GPR119KCNH2NPC1RAB9AKDM4E | |
| SCHEMBL1687202 | 0.79 | NPC1 (0.38) | GPR119NPC1RAB9AKDM4EPDE8B | |
| SCHEMBL12409004 | 0.79 | GPR119 (0.50) | GPR119NPC1RAB9AKDM4EKIT | |
| SCHEMBL25190421 | 0.78 | SMO (0.40) | GPR119NPC1RAB9AKDM4EPDE8B | |
| SCHEMBL24921761 | 0.78 | HDAC3 (0.46) | GPR119NPC1RAB9AKDM4EKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320129-A1 | GPR119 AGONISTS | Kallyope, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |