Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086563 | 0.90 | GPR119 (0.47) | GPR119KCNH2CYP3A4KITAOC3 | |
| SCHEMBL24437753 | 0.81 | GPR119 (0.51) | GPR119KCNH2CYP3A4AOC3KDM4E | |
| SCHEMBL27086530 | 0.81 | GPR119 (0.43) | GPR119KCNH2CYP3A4KITAOC3 | |
| SCHEMBL21791392 | 0.80 | GPR119 (0.45) | GPR119KCNH2CYP3A4AOC3SMO | |
| SCHEMBL24921761 | 0.74 | HDAC3 (0.46) | GPR119KITKDM4EALDH1A1HPGD | |
| SCHEMBL11957018 | 0.74 | GPR119 (0.46) | GPR119KDM4EPDE8BNPC1RAB9A | |
| SCHEMBL24920518 | 0.73 | POLB (0.49) | GPR119AOC3KDM4EALDH1A1HPGD | |
| SCHEMBL12409004 | 0.72 | GPR119 (0.50) | GPR119KITKDM4EPDE8BNPC1 | |
| SCHEMBL14314910 | 0.71 | GPR119 (0.58) | GPR119KCNH2CYP3A4 | |
| SCHEMBL19454659 | 0.70 | NPC1 (0.51) | GPR119KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022216709-A1 | GPR119 AGONISTS | KALLYOPE, INC. (US) | 2022-10-13 | — | — | WO | disclosed |