SCHEMBL2708786

SCHEMBL2708786

O=C(O)c1ccc(Oc2ccc(C34CC5CC(C3)CC(c3ccc(Oc6ccc(C(=O)O)c(C(=O)O)c6)cc3)(C5)C4)cc2)cc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
HIF1A Q16665 3/20 0.43
EPAS1 Q99814 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RAB9A P51151 1/20 0.42
ESR1 P03372 1/20 0.42
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PGR P06401 2/20 0.40
ALDH1A1 P00352 2/20 0.40
SERPINE1 P05121 1/20 0.40
HPSE Q9Y251 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710090 0.84 MEN1 (0.44) POLBMEN1KMT2ARAB9APGR
SCHEMBL2747023 0.83 HIF1A (0.46) HIF1AEPAS1MEN1KMT2ARAB9A
SCHEMBL2747045 0.82 AKR1C3 (0.56) POLBHIF1AEPAS1RAB9ALMNA
SCHEMBL31544680 0.82 AKR1C3 (0.56) POLBHIF1AEPAS1RAB9ALMNA
SCHEMBL2746775 0.81 KDM4E (0.50) HIF1AEPAS1MEN1KMT2ARAB9A
SCHEMBL2707830 0.80 HIF1A (0.47) POLBHIF1AEPAS1MEN1KMT2A
SCHEMBL2708781 0.80 POLB (0.44) POLBHIF1AEPAS1KMT2ALMNA
SCHEMBL2709745 0.80 POLB (0.49) POLBMEN1KMT2ALMNAALDH1A1
SCHEMBL2707997 0.80 POLB (0.41) POLBHIF1AEPAS1MEN1KMT2A
SCHEMBL2708799 0.79 HIF1A (0.43) POLBHIF1AEPAS1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed