SCHEMBL2708799

SCHEMBL2708799

O=C(O)c1ccc(Oc2ccc(C34CC5CC(CC(C5)C3)C4)cc2-c2cc(C34CC5CC(CC(C5)C3)C4)ccc2Oc2ccc(C(=O)O)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 5/20 0.43
EPAS1 Q99814 3/20 0.43
SERPINE1 P05121 2/20 0.42
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 3/20 0.40
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
KDM4E B2RXH2 2/20 0.39
PYGL P06737 2/20 0.38
PYGM P11217 1/20 0.38
LMNA P02545 2/20 0.38
NR1I2 O75469 1/20 0.38
PGR P06401 1/20 0.38
RARA P10276 1/20 0.38
HSPD1 P10809 1/20 0.38
RARB P10826 1/20 0.38
RARG P13631 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710722 0.85 HIF1A (0.47) HIF1AEPAS1SERPINE1KMT2AMEN1
SCHEMBL16046931 0.82 RARB (0.46) HIF1AEPAS1KMT2AMEN1POLB
SCHEMBL2707994 0.82 HIF1A (0.42) HIF1AEPAS1SERPINE1KMT2AMEN1
SCHEMBL2707997 0.81 POLB (0.41) HIF1AEPAS1SERPINE1KMT2AMEN1
SCHEMBL28289972 0.81 KMT2A (0.54) HIF1AEPAS1SERPINE1KMT2AMEN1
SCHEMBL2709132 0.81 RARB (0.45) HIF1AEPAS1KMT2AMEN1POLB
SCHEMBL2708786 0.79 POLB (0.48) HIF1AEPAS1SERPINE1KMT2AMEN1
SCHEMBL2708118 0.77 ALDH1A1 (0.58) HIF1AEPAS1KMT2AMEN1RAB9A
SCHEMBL2709265 0.77 KMT2A (0.48) HIF1AEPAS1KMT2AMEN1RAB9A
SCHEMBL2711005 0.76 KMT2A (0.47) HIF1AEPAS1SERPINE1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed