SCHEMBL2708995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2708176	0.89	MEN1 (0.43)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL2707501	0.87	TLR7 (0.47)	ALDH1A1TLR7LMNATSHR
	SCHEMBL2707291	0.85	ALDH1A1 (0.40)	KDM4EL3MBTL1ALDH1A1HPGDMEN1
	SCHEMBL2682348	0.83	TLR7 (0.42)	KDM4EL3MBTL1ALDH1A1HPGDMEN1
	SCHEMBL2682714	0.79	KDM4E (0.42)	KDM4EL3MBTL1ALDH1A1HPGDMEN1
	SCHEMBL2707399	0.77	KDM4E (0.38)	KDM4EALDH1A1HPGDMAPTPDE10A
	SCHEMBL2707491	0.77	TLR7 (0.48)	KDM4EALDH1A1HPGDKMT2ATLR7
	SCHEMBL2706419	0.77	CYP1A2 (0.40)	KDM4EALDH1A1HPGDTLR7GPR3
	SCHEMBL2709438	0.77	KDM4E (0.40)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL1895853	0.76	TLR7 (0.53)	MEN1KMT2APDE10ATLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.