Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Chloride SCHEMBL29051489 | 0.91 | CA2 (0.46) | CA2CA12CA1CA7CA9 | |
| SCHEMBL356412 | 0.83 | KDM4E (0.59) | ALDH1A1TSHRMAPK1PDE4AKDM4E | |
| SCHEMBL1379795 | 0.83 | PDE4A (0.54) | ALDH1A1TSHRMAPK1PDE4AKDM4E | |
| SCHEMBL15915111 | 0.83 | CA2 (0.39) | CA2CA12CA1CA7CA9 | |
| SCHEMBL16956289 | 0.83 | SMN1; SMN2 (0.43) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2811538 | 0.82 | CA2 (0.41) | CA2CA12CA1CA7CA9 | |
| SCHEMBL6291782 | 0.81 | PDE4A (0.53) | CA2CA12CA1CA7CA9 | |
| SCHEMBL16953063 | 0.81 | CYP1A2 (0.40) | CA2CA12CA1CA7CA9 | |
| SCHEMBL16954143 | 0.81 | CYP1A2 (0.40) | CA2CA12CA1CA7CA9 | |
| SCHEMBL16954400 | 0.81 | PDE4B (0.46) | CA2CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 16418 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039690-B1 | A SUBSTANTIALLY DIASTEREOMERICALLY PURE PHOSPHORAMIDOCHLORIDATE, A METHOD AND A PHARMACEUTICAL COMPOSITION | EISAI R&D MAN CO LTD (JP) | 2024-07-17 | — | — | EP | claimed |
| CN-110799520-B | Method for synthesizing peptides containing N-substituted amino acids | 中外制药株式会社 | 2024-07-12 | — | — | CN | claimed |
| CN-118302422-A | Substituted N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290406-A | Method for synthesizing tetrahydrofuran compound by organic catalysis | 中国海洋大学 | 2024-07-05 | — | — | CN | claimed |
| US-20240218022-A1 | ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-04 | — | — | US | claimed |
| EP-4157834-B1 | N-(1-CYANO-PYRROLIDIN-3-YL)-5-(3-(TRIFLUOROMETHYL)PHENYL)OXAZOLE-2-CARBOXAMIDE DERIVATIVES AND THE CORRESPONDING OXADIAZOLE DERIVATIVES AS USP30 INHIBITORS FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION | MISSION THERAPEUTICS LTD (GB) | 2024-07-03 | — | — | EP | claimed |
| CN-118271233-A | Nilaparil manufacturing method | 特沙诺有限公司 | 2024-07-02 | — | — | CN | claimed |
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| US-20240209029-A1 | ADIPONECTIN GLYCOPEPTIDES AND COMPOSITIONS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2024-06-27 | — | — | US | claimed |
| EP-4387673-A1 | PROCESS FOR THE PREPARATION OF PEGYLATED ADRENOMEDULLIN, ITS INTERMEDIATES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2024-06-26 | — | — | EP | claimed |
| US-4232014-A | AMIDOALKYLINDANS | MARION LABORATORIES, INC. (US) | 1980-11-04 | — | — | US | claimed |
| US-4187220-A | New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1980-02-05 | — | — | US | claimed |
| US-4179507-A | NEUROMUSCULAR PARALYSIS, MUSCLE RELAXANTS, ISOQUINOLINE DERIVATIVES | BURROUGHS WELLCOME CO. (US) | 1979-12-18 | — | — | US | claimed |
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | claimed |
| US-4098705-A | ADDITIVE FOR LUBRICANTS | ASAHI DENKA KOGYO K.K. (JP) | 1978-07-04 | — | — | US | claimed |
| US-4096153-A | Arylene-bis-tetrazole-5-carboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-06-20 | — | — | US | claimed |
| US-4075340-A | ANTIINFLAMMATORY, ANTIARRYTHMIC, ANTICOAGULANTS | PARCOR (FR) | 1978-02-21 | — | — | US | claimed |
| US-3954774-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-05-04 | — | — | US | claimed |
| US-3936454-A | ANTIANGINAL, BRONCHODILATOR | WARNER-LAMBERT COMPANY (US) | 1976-02-03 | — | — | US | claimed |
| US-3932423-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES (JA) | 1976-01-13 | — | — | US | claimed |